i use a 22-250 and its just a great round for yotes and as for calls get a rabbit distress and a howler call just to start with. stay scentless as well yotes will work the wind better than any deer, most of all if you shoot one start calling again. dont think that the yotes know the diffrence from a thunder clap or a gun unless they have been shot at before.ive killed several just after the first shot so have fun