Im shooting handloaded V-Max in my Ruger M77, .243. It will stack them. However, it shoots high and right of the Hornady 100grn BTSP's I load. Still, they group great and will get the job done at ranges well over 200yds. I wouldnt hesitate to shoot mine over 300 yards on a yote.
It actually depends on the rifle. Two of the same model and cal wont necessarly shoot the same type of bullet the same. I had a Remington 700 in ADL that wouldnt shoot 150grn corelokt at all. However, bump that to 180grn and they would stack on top of each other.