Like I mentioned in previous posts, I facilitate smoking cessation classes, I'm also a Registered Respiratory Therapist. The FDA has tested the ingredients in the cartridges, but not the effects of using the product, or or smoking cessation rates of success with the product. However, there are some Physician groups that feel they may be a legitamit nicotine replacement therapy, and are urging the FDA to reclassify. Unlikely IMO. Frankly due to the lack of regulation and somewhat shady manufacturers, I'd be hesitant to use or recomend e-cigs. I'd be concerned about infection, inhaling aerosol of any sort dramtically raises the chances of infection. And keeping something like this sterile, seems just about impossible.